Genocide • 20260519

Settela Steinbach — The Girl with the Headscarf • 1MEMO_20260519_1 • Settela•Com • Frame from camera original film reel of the Westerborkfilm (1).

On May 19, 1944, at the Westerbork transit camp, a glimpse of Sinti girl Settela Steinbach wearing a headscarf appears between the sliding doors of a cattle car awaiting deportation to Auschwitz (1,2,3).
In May 1945, her father, Moeselman Steinbach, wrote to “Repatriation” in the Netherlands: “…I very politely request you to inform me whether my wife and 10 children have arrived, or only children (Gypsy children) from the Auschwitz concentration camp in Poland.” (4).

The 9-year-old dutch Sinti-girl Anna Maria ‘Settela’ Steinbach peeks outside , at the last moment just before the sliding door is closed , standing inside a cattle car with 74 people on May 19 , 1944 in the Westerbork transit camp in Holland , when this deportation train leaves for Auschwitz-Birkenau – where Settela is murdered a few months later in one of the gas chambers (5).

While Settela peeks outside , her mother cries behind her in that cattle car : “Get out of there, or soon your head gets in between!”

She is wearing a headscarf made from a torn sheet because the Nazis shaved her head upon arrival at Westerbork transit camp on May 16, 1944, following the “Gypsy raid” carried out that same day at the Zwaaikom caravan site in Eindhoven, the Netherlands (6).

Settela Film • 20220630

Settela was filmed only a few seconds by the Jewish prisoner filmmaker Rudolf Breslauer as part of a documentary film being made in 1944 on the Westerbork camp .
Those seconds , also in slow-motion are shown in the 2022 Settela Film • 20220630 (7)

The toddler Settela in the arms of her older sister Elisabeth Steinbach at the Heksenberg Sinti caravan site in 1935 • Photo Jan de Jong • 1MEMO_20260518_4

Anna Maria (‘Settela’) Steinbach was born 23 December 1934 in Buchten, Netherlands, and photographed at age ~1 , in the arms of her older sister Elisabeth Steinbach, with others of the Steinbach family, and other families, at the nearby Sinti caravan site ‘Heksenberg’, October 1935, by photographer Jan de Jong (8) • 1MEMO_20260518_4

Settela was deported together with her brothers and sisters (Willy “Celestinus”, Willem, Elisabeth, Johanna, Philibert, Florentina, Willem, Anna), and mother Toetela (Emilia) Steinbach (born 23 March 1902 in Antwerp, Belgium), with other Steinbach and other nomad families – all together ca 245 Sinti and Roma and ca 450 Jews – on May 19th 1944 from the dutch Camp Westerbork to the Auschwitz and Bergen-Belsen camps (5,6).

Toetela’s eldest child Moekela (Magdalena; born 14 Sep 1922) had gone to Belgium and had been deported earlier – 15 Jan 1944 – with her 6 months old baby Jeanette – Toetela’s granddaughter – on the Z-Transport from transit camp Kazerne Dossin in Mechelen to Auschwitz, were they were murdered on arrival.

Settela’s father Heinrich (‘Moeselman’) Steinbach (born Nov 11, 1901 in Gründorf in Germany) died alone of grief June 6, 1946 in Maastricht in the Netherlands – his wife and 10 children had not survived the camps.

To : “Repatriation” in Maastricht (Netherlands) — “Dear Sirs, I very politely request you to inform me whether my wife and 10 children have arrived, or only children (Gypsy children) from the Auschwitz concentration camp in Poland.
From May 15, 1944, my children and wife were taken there; no Jews. And Weiss had to come along too. — Heinrich Steinbach. Caravan site Eindhoven , North Brabant” • 1MEMO_20260519_2 • Settela•Com

One year earlier , May 22, 1945, two weeks after the liberation of Holland, Heinrich Steinbach — living at the caravan site in Eindhoven (North Brabant, Netherlands) — inquires about the fate of his wife and ten children on a postcard written to the “Repatriation” in Maastricht (Netherlands). The text on the postcard reads — translated from dutch (4) :

“Dear Sirs, I very politely request you to inform me whether my wife and 10 children have arrived, or only children (Gypsy children) from the Auschwitz concentration camp in Poland.

From May 15, 1944, my children and wife were taken there; no Jews. And Weiss had to come along too.

Heinrich Steinbach. Caravan site Eindhoven N.B.”

Notes

1 – Settela Steinbach in Westerbork Film 🎦 2021 | 20220302 | Michel van der Burg | Settela•Com | ISSN 2949-9313 (accessed 2026 May 18) URL: https://www.youtube.com/watch?v=ZiLNDziwEtc&t=1012s

4 – May 1945 Postcard Heinrich Steinbach • 1MEMO_20260519_2 • Settela•Com | ISSN 2949-9313 | Source : Collectie HCL, archief Militair Gezag, Maastricht.
‘Moeselman’ Heinrich Steinbach — living at the caravan site in Eindhoven (North Brabant, Netherlands) — inquires about the fate of his wife and ten children on a postcard written to the “Repatriation” in Maastricht (Netherlands). The dutch text on the postcard reads :
“Geachte Heeren, Ik verzoek u zeer beleeft om mijn te willen berichten op mijn vrouw en 10 kinders aan gekomen zein of alleen kinders (zigeunerkinders) uit contrasie kamp uaschwietsch Polen.
Van 15 mei 1944 zein mijn kindeers en vrouw naar toe gebracht, geen joden. En ook Weiss moet ook mee komen. Heinrich Steinbach. Woonwagenkamp Eindhoven N.B.”

6 – ‘Zigeunerrazzia’ 16 mei 1944. Peter Jorna. Stichting 18 September (Eindhoven) URL https://stichting18september.nl/zigeunertransport/

8- Sinti Caravan Site • 20260518 | Michel van der Burg | Settela•Com | ISSN 2949-9313 | URL https://settela.com/2026/05/18

TAGS #Settela #girl #headscarf #Steinbach #Westerborkfilm #Westerbork #Breslauer #Roma #Sinti #gypsy #zigeuner #nomad #caravan #razzia #raid #Eindhoven #postcard #Holocaust #Porajmos #genocide #children #camp #deportation #Jew #Netherlands #railcar #train #station #transitcamp #UNESCO #film #letter #Heksenberg #Zwaaikom #Auschwitz #SettelaCom #MiraclesMedia #michelvanderburg

Liberation • 1MEMO_20260508

Liberation • 1MEMO_20260508 • Michel van der Burg • Miracles•Media • Cheering crowds greet British troops entering Brussels, 4 September 1944 . TakeNode 43cdc95e-4db6-44db-bd5b-fec92f198f86

Celebrating crowds, while the Allied troops drive the Germans out of the city, Sunday 3 September 1944 in Brussels, Belgium .

Source Image : BUM20200418_38 • Miracles.Media (BU483 , WikiMedia Commons)

Source Video : Brussels Liberated • @1MEMO_20200415 • Michel van der Burg • Miracles.Media • TakeNode 00e3f7fb-2455-4239-b1da-120f31e85fc3 • From : The Year 1944 United Newsreel ( 208 UN 1034 USHMM RG-60.3053 | Film ID: 2396 )
#liberation #celebration #occupation #street #crowd #dance #Brussels #Belgium #war #ww2 #MiraclesMedia #allies

Yodeling • Tyrolean Folksy Hootenanny 2026 #1 • Via Romea #53 • @1MEMO_20260327

Yodeling • Tyrolean Folksy Hootenanny 2026 #1 • Via Romea #53 • @1MEMO_20260327 • Michel van der Burg • Miracles•Media • TakeNode 2e07f99b-1bbc-48e9-aac6-02baec4a4339 •
Simple yodel song, celebrating spring at the Hoangascht – Hootenanny – along the Jakobsweg route — also the Via Romea here — in Gasthof Turmbichl, Vill, Tyrol, Austria, March 2026

Casual get-together of locals singing and playing folk & schlager music. for more of this Tyrolean folksy music , check it out at my channel, searching for ‘Hoangascht’ • https://www.youtube.com/@michelvanderburg/search?query=Hoangascht

Compilations
Viller Musikanten Hoangascht • @1MEMO 20180321 • https://youtu.be/2T8kc5vSGuM Recorded March 2016.

Inge’s Tyrolean Folk Music • @1MEMO 20250323 • https://youtu.be/6kUpDvVesKU

More Tyrol musical film work in the YouTube Playlist ‘Tyrol Music’ – https://youtube.com/playlist?list=PL_SggYHVHwj3eL6D8AzUm3o84OrU1JX_7

#music #folk #hoangascht #hootenanny #Vill #Innsbruck #Via #Romea #Tirolensis #pilgrim #route #path #Tyrol #Jakobsweg #Camino #Santiago #Alps #musicvideo #art

Successful Islet Transplantation After Purification in Iodixanol-UWS • IPITA 1999 Sydney • @1MEMO 20260326

Pig islets after isolation in Iodixanol-UWS • 7th IPITA World Congress 1999 • 1MEMO_20260326_1 • Michel van der Burg • Miracles•Media • TakeNode 467e773c-fc4b-416e-99d5-c88df76ddff4 • Presentation by Michel van der Burg (Notes #5).

Shortly after our introduction at the previous IPITA World Congress, September 1997 in Milan (Italy) of the novel Iodixanol -UWS solution for isolation of juvenile pig islets (1), we reported successful xeno-transplantation in diabetic Swiss nude (immunodeficient) mice of adult pig islets isolated with this Iodixanol -UWS method, first Tuesday, Jan 27, 1998 at the 17th Workshop of the AIDSPIT Study Group in Igls, Austria (2a), and next April 1998 at the 10th Congress of the Dutch Transplantation Society (2b). We had started these first pig islet xenotransplants in mice also that same month of September 1997 — highlighted in the image below ( 1MEMO_20260326_12 )

First pig islet xeno transplants in mice • 1MEMO_20260326_12 • Michel van der Burg • Miracles•Media • TakeNode d4cc1f11-c107-4011-8dbe-9649da76e3ff • September 1997, we performed our first two pig islet xenotransplants into diabetic Swiss nude mice. The pig islets were isolated with Iodixanol-UWS from an adult pig pancreas (top panel: sample of the islets stained red with dithizone, fresh after isolation and purification). These pure islets were kept 1 week in a culture solution, before transplantation of the islets by injecting the islets under the kidney capsule in 2 diabetic Swiss nude mice. Both mice had normal blood glucose from the day one after transplantation, and upon removal of the kidneys for examination at 1 month after transplantation , we observed excellent islets under the kidney capsule , as shown in the bottom panel image of a kidney section stained with H&E (note : the inserted portrait of the Swiss nude mouse, actually is our #7 pig islet xenograft, alive and kicking, Dec 1997).

Starting with the September 1997 IPITA meeting in Milan, I was sharing in detail the materials and methods of our purification procedure, face to face and in post-congress correspondence, with my colleagues of the other islets centers, thus facilitating fast implementation by Bernhard Hering and Shinichi Matsumoto of the Iodixanol-UWS purification method in the Minneapolis islet center, contributing to their successful single-donor pig islet allo-transplants, as reported by Shinichi Matsumoto May 1998 at the 24th Annual Scientific Meeting of the American Society of Transplant Surgeons, in Chicago (3).

That month, May 1998, I also finished the first series of human islet purifications with the novel Iodixanol-UWS density gradient, while working on human islet isolations in the Miami team at the Diabetes Research Institute (Scientific director Prof. C. Ricordi, MD) of the University of Miami , in Miami, Florida, USA . The successful outcome of the human islet purification work done in Miami was reported from January 1999 in a talk and poster presentations , including a poster presentation at the 7th World Congress of the International Pancreas & Islet Transplant Association, Sydney (Australia) August 1999 (4).

Viability of Fresh vs Cultured Pig Islets for Transplants • 1MEMO_20260326_2

Slideshow presentation by Josephine Rijkelijkhuizen • 7th IPITA World Congress 1999 • Viability of Fresh vs Cultured Pig Islets for Transplants • 1MEMO_20260326_2 • Michel van der Burg • Miracles•Media • TakeNode 7164b724-65bf-4d3f-8a40-89b188957d1b • Notes #6

1MEMO_20260326_3 Download

Handout • PDF (Viability of Fresh vs Cultured Pig Islets for Transplants)
7th IPITA World Congress 1999 • 1MEMO_20260326_3 • Michel van der Burg • Miracles•Media • TakeNode 995e90b3-d797-435c-a510-00a0e35bc424 • Handout presentation by Josephine Rijkelijkhuizen (Notes #6).

In our oral presentations at the 7th World Congress of the International Pancreas & Islet Transplant Association, Sydney (Australia) August 1999, we demonstrated both the complete recovery of pure intact pig islets during isolation in UWS and purification in the novel solution of Iodixanol (Optiprep) in UWS, and the superior viability of these islets following short-term storage in culture solution (‘culture’) , allowing successful xeno transplantation of the pig islets in mice (5,6), rats (7), and monkeys (8) .

The 7th IPITA congress abstracts were published online only at the official website of the IPITA, in Oxford at the time (www.jr2.ox.ac.uk/ipita), and cannot be retrieved now (9). However, I kept an archive with photocopies of our abstracts published in print in the Abstract Book of the 7th IPITA , posted below.

One of our papers was included among the top 10 papers selected for submission of a full paper in a special issue of the journal Cell Transplantation — see below.

Josephine Rijkelijkhuizen at the 7th IPITA World Congress 1999 • 1MEMO_20260326_4 • Photo by Michel van der Burg • Miracles•Media • TakeNode 0c2ef6fb-bdff-4895-9dde-eb242f957cb9

Top 10 Paper

Our study — collaborative research of our Surgery Department (LUMC), and workers of the Biomedical Primate Research Centre in Rijswijk (Netherlands) — presented by our student researcher Josephine Rijkelijkhuizen, showing that cultured pig islets, isolated and purified in Iodixanol-UWS, can be transplanted without hyperacute rejection in cynomolgous monkeys , was selected in the top 10 outstanding studies at the memorable Sidney World Congress of the International Pancreas & Islet Transplant Association (9) , and the full paper included in a special issue of the journal Cell Transplantation (10).

Our studies , together, demonstrated the importance of both donor organ selection (choosing adult organs), selection of non-toxic, endotoxin-free media, such as iodixanol and UWS, as the isolation solutions, and selection of islets that survive storage in culture, for a successful outcome after transplantation in this difficult model of xeno-transplantation, grafting porcine islets in other species.

Notes

1) Innovative Islet Purification in Iodixanol-UWS • IPITA 97 • Michel van der Burg • Miracles.Media • @1MEMO 20250128 • URL michelvanderburg.com/2025/01/28/

2a) Iodixanol-UWS Purification for Porcine Islet Transplantation • AIDSPIT 1998 • Michel van der Burg • Miracles.Media • @1MEMO 20250131 • URL michelvanderburg.com/2025/01/31/

2b) Fresh vs Cultured Pig Islets for Xenografts • NTV Bootcongres 1998 • Michel van der Burg • Miracles.Media • @1MEMO 20250201 • URL michelvanderburg.com/2025/02/01/

3) Matsumoto S, Zhang H J, Gilmore T, van der Burg MPM, Sutherland DER, Hering BJ. Large scale isopycnic islet purification utilizing non-toxic, endotoxin-free media facilitate immediate single-donor pig islet allograft function (Abstract). Transplantation 1998; 66: S30 • 1MEMO_20260326_10 • Michel van der Burg • Miracles.Media • TakeNode a7e8ec21-1757-45f4-90c6-1a5f457e0d9f , View/download PDF below.

1MEMO_20260326_10 Download

Presentation at the 24th Annual Scientific Meeting of the American Society of Transplant Surgeons, Chicago (USA) May 1998. 24th ASTS Program book, Abstract #A-120 • 1MEMO_20260326_5 • Michel van der Burg • Miracles.Media • TakeNode 9efdd5cb-f6da-4dec-b9d9-63cf0b254b30

4) Van der Burg MPM, Ranuncoli A, Molano R, Kirlew T, Ringers J, Bouwman E, Terpstra OT, Ricordi C. New powerful tool for human islet purification: OptiPrep-UWS? 7th World Congress of the International Pancreas & Islet Transplant Association, Sydney (Australia) August 22–25, 1999. Abstract in Programme and Abstract Book, page 169, P298 . In : New Powerful Tool For Human Islet Purification • OptiPrep-UWS ? • IPITA 1999 Sydney • @1MEMO 20260325 • Michel van der Burg • Miracles.Media • URL michelvanderburg.com/2026/03/25/

5) Van der Burg MPM, Rijkelijkhuizen JKRA, Zwaan RP, Bouwman E. Recovery of adult pig islets during isolation using Liberase vs collagenase-P, purification in OptiPrep-UWS, and culture for transplantation in nude mice. 7th World congress of the International Pancreas & Islet Transplant Association, Sydney (Australia) August 22–25, 1999. Programme and Abstract Book, page 164, #281 . 1MEMO_20241203_3 • In : Iodixanol Purification of Porcine Islets • Sydney IPITA 1999 • 1MEMO 20241203 • Michel van der Burg • Miracles.Media • TakeNode 64ace253-d25b-4b6d-af5b-08060712c471 • URL michelvanderburg.com/2024/12/03/

6) Rijkelijkhuizen JKRA, Bouwman E, Van der Burg MPM. Pre-transplant culture markedly improves pig islet graft survival in nude mice. 7th World congress of the International Pancreas & Islet Transplant Association, Sydney (Australia) August 22–25, 1999. Programme and Abstract Book, page 117, #162 . 1MEMO_20260326_6 • Michel van der Burg • Miracles.Media • TakeNode 5ce0c54f-a6a1-4cc9-8f68-9a1cd723badf

7) Rijkelijkhuizen JKRA, Van der Burg MPM, Bouwman E. Longterm survival of porcine islets in the rat. 7th World congress of the International Pancreas & Islet Transplant Association, Sydney (Australia) August 22–25, 1999. Programme and Abstract Book, page 112, #152 . 1MEMO_20260326_7 • Michel van der Burg • Miracles.Media • TakeNode bc9a48ee-23ff-48f1-ab2c-5bcef071ebaa

8) Rijkelijkhuizen JKRA, Bouwman E, Van der Burg MPM, Ringers J, Ossevoort MA, Kuhn EM, Frost P, Jonker M. Successful suppression of the early rejection of pig islets in monkeys. 7th World congress of the International Pancreas & Islet Transplant Association, Sydney (Australia) August 22–25, 1999. Programme and Abstract Book, page 144, #231 . 1MEMO_20260326_8 • Michel van der Burg • Miracles.Media • TakeNode 29bb03b4-8b02-4aa9-9b33-715ca006c28e

9) Ricordi C. Prime Time for Pancreas and Islet Transplantation at the Turn of the Millennium. Cell Transplant. 2000 Nov;9(6):853-855. doi: 10.1177/096368970000900611. PMID: 28886292. URL https://journals.sagepub.com/doi/epdf/10.1177/096368970000900611 (Free Full Paper)

10) Rijkelijkhuizen JK, Bouwman E, van der Burg MP, Ringers J, Ossevoort MA, Kuhn EM, Frost P, Jonker M. Successful suppression of the early rejection of pig islets in monkeys. Cell Transplant. 2000 Nov-Dec;9(6):909-12. doi: 10.1177/096368970000900618. PMID: 11202577. URL https://journals.sagepub.com/doi/epdf/10.1177/096368970000900618 (Free Full Paper) • Collaborative research From Biomedical Primate Research Centre (M.O., E.M.K.,
J.W., K.H., M.J.), Rijswijk, and Leiden University Medical Centre (J.K.R.A.R., J.R., M.vdB., E.B.), Leiden, The Netherlands .

Sydney Convention Center • 1MEMO_20260326_9 • Michel van der Burg • Miracles.Media • TakeNode 1ce6bbf2-adf1-4ce3-8c69-cd2d1339be81 • Sydney Convention Center – Darling Harbour (demolished in 2013)

Cultured pig islets for xenotransplantation • 1MEMO_20260326_11 • Michel van der Burg • Miracles•Media • TakeNode bd15f087-29cd-4e99-a555-9fbfbd1729bc • Reflection contrast microscopy (ultrathin section) of 1-week cultured pig islets . During storage in culture remodeling of the isolated islets occurs, showing rounded islets , with some central necrosis after prolonged culture. Transplantation of 1250 islets (IEQs) from this same 1-week cultured pig islet preparation cured all (n=3) diabetic nude mice indefinitely (over 150 days). In contrast transplants of freshly isolated islets (not cultured) using the same dose of 1250 islets (IEQs) from this same islet preparation, did not cure diabetic nude mice (n=2). Adult pig pancreas procurement by Michel van der Burg from the nearby Westgeest slaughterhouse (in Zoetermeer) facility for large sows processing by Ballering Export (Son, Netherlands; a company of second cousins, of mine).
. Islet isolation (using Iodixanol-UWS) and transplants team work by Josephine Rijkelijkhuizen and Michel van der Burg, Leiden Islet Laboratory (LUMC), May 1998. Reflection contrast microscopy by Frans A. Prins and Michel van der Burg. Not previously published data and photo by Michel van der Burg.

#IPITA #Sydney #surgery #DRI #Miami #clinical #laboratory #purification #optiprep #iodixanol #density #gradient #UWS #pancreas #human #pig #rat #mouse #monkey #xeno #islets #islet #Langerhans #isolation #UW #university #Wisconsin #transplantation #diabetes #man #history #Holland #Netherlands #Leiden #hospital #LUMC #1memo #michelvanderburg #Rijkelijkhuizen #Matsumoto #Hering #Minneapolis #Ricordi

Citation info : Successful Islet Transplantation After Purification in Iodixanol-UWS • IPITA 1999 Sydney • @1MEMO 20260326 • Michel van der Burg • Miracles.Media • URL michelvanderburg.com/2026/03/26/

24th AIDPIT Workshop Igls • @1MEMO 20260125

Short impression of the 24th Workshop of the AIDPIT Study Group (Artificial Insulin Delivery, Pancreas and Islet Transplantation), in Igls (Innsbruck) Austria, 23-25 January 2005.

Video from January 25th featuring :

(i) the Igls Congress park ;

(ii) the morning opening lecture by Mathias Brendel, with chairs Bart Keymeulen (Brussels, Belgium) and Mathias Brendel (Giessen, Germany), and, in the lecture hall : president Annika Tibell (Sweden) and honorary member Reinhard Bretzel (Germany) ;

(iii) a lunch time meeting with José Oberholzer (Chicago, USA) … not familar yet 😉 with that new little Sony T1 camera with a periscopic lens inside .. ;

(iv) one of the afternoon discussion groups (Clinical Islet Transplantation) ;

(v) clips from the plenary oral abstract session with chairs Karin Ulrichs (Germany) and Richard Smith (Bristol , UK) and lectures by Norma Sue Kenyon (Miami , USA) and Piero Marchetti (Pisa, Italy) with discussion by Daniel Brandhorst.

Notes

AIDPIT was known first as AIDSPIT, short for : Artificial Insulin Delivery Systems, Pancreas and Islet Transplantation.
The AIDSPIT study group of the European Association for the Study of Diabetes (EASD) was established in the early 1980s.
In 2000 the acronym AIDSPIT was replaced by ‘AIDPIT’, in order to avoid confusion with the AIDS disease.

The annual meetings are generally held in the little town of Igls, close to Innsbruck in Austria — the first years, early in February, and next, late in January. Once, in the 1990s (following a discussion ‘…why always in Igls?’, the meeting was held in Amsterdam.
From 2011, the annual workshops of AIDPIT continued as a joined meeting with the EPITA — the European Pancreas and Islet Transplant Association — part of the European Society for Organ Transplantation (ESOT).
From 2024 — following the 12th EPITA Symposium & 41st AIDPIT Workshop in 2023 — this symposium is referred to as the EPITA Symposium.

The original film (2016) was uploaded to Vimeo (size 640×480), and posted Jan 25, 2016 (20160125) at blogging site 1-memo.com , URL https://1-memo.com/2016/01/25/24th-aidpit-workshop-igls/

A second, remastered, video edition (2022) was produced by upscaling the original video file (converted to size 1920 × 1440) and adding a caption, and uploaded to YouTube Jan 25, 2022.

This second edition is published now – Jan 25th 2026 – as part of the Science series of posts at my site michelvanderburg.com, started in 2022 to make available online a portfolio of the science section of my CV, a project I hope to finish soon… in a few months.

Portfolio – Science : https://michelvanderburg.com/category/science/

#AIDPIT #EPITAsymposium #Igls #Innsbruck #Tyrol #history #ESOT_EPITA ##AIDSPIT #Austria #islet #Langerhans #isolation #transplantation #pancreas #diabetes #insulin #michelvanderburg #symposium #EASD #ESOT #workshop #EPITA #science

Citation info : 24th AIDPIT Workshop Igls • Michel van der Burg • Miracles•Media • @1MEMO 20260125 • TakeNode 3baced38-ee79-4127-932d-0136293529e7 • URL https://michelvanderburg.com/2026/01/25

Glycemic control mechanisms after canine islet autografting • IPITA 1995• @1MEMO 20251204

Glycemic control mechanisms after canine islet autografting • IPITA 1995 • Michel van der Burg • Miracles.Media • @1MEMO 20251204_1 • Talk, Tuesday June 20, 1995 at 10:30, 5th IPITA, Eden Roc Resort Hotel, Miami Beach, FL (USA) • Digitally remastered by author, publisher, Michel van der Burg • TakeNode 5227c200-e029-4406-b344-15350fe3b93d • #GLP1 #GIP #diabetes #islets #transplant

Pioneer work on GLP-1 and GIP incretin hormones

Slideshow (digitally remastered) of my talk Tuesday June 20, 1995 at 10:30, at the 5th International Congress on Pancreas and Islet Transplantation (IPITA), in Miami Beach, FL (USA). My first talk at a world congress presenting the outcome of all our detailed metabolic studies in our preclinical model of canine islet autotransplantation , including our pioneer work on the incretin effects of the gut hormones GLP-1 (glucagon-like peptide-1) and GIP (Glucose-dependent Insulinotropic Polypeptide) — now, in 2025, well-known from the drugs that mimic the action of these natural hormones, to treat type 2 diabetes and obesity, by stimulating insulin release, improving blood sugar control, and reducing appetite.

May 1992 we were the first to show direct potentiation of the insulin response from isolated islets by (near-)physiological doses of both the gut hormones GLP-1 and GIP during perifusion (in vitro) of canine islets at 7.5-10 mM glucose levels (1,2), and January 1994 we next confirmed the incretin effect of a (near-)physiological dose of GLP-1 after canine islet transplantation , in a poster presented at the 13th Workshop of the AIDSPIT (aka AIDPIT) Study Group , Igls, Austria, January 23–25, 1994 (3).

Background of the work was posted earlier this year (4) and the work was published Nov 1994 in my PhD thesis Pancreatic islet transplantation , available online (5).

Welcome Reception 5th IPITA on Sunday 18 June 1995, at the congress venue , the Eden Roc Resort Hotel, in Miami Beach, FL (USA) • Michel van der Burg • Miracles.Media • @1MEMO 20251204_2 • TakeNode 8eb04df1-8280-4de3-a206-4b63413c3025

June 1995, 5th IPITA Talk

Tuesday June 20, 1995 at 10:30, at the 5th International Congress on Pancreas and Islet Transplantation (IPITA), in Miami Beach, FL (USA), was my first talk at a world congress presenting the outcome of all our detailed metabolic studies in the canine islet transplants , including the incretin effect of GLP-1, and also our findings with isolated canine islets during perifusion, in vitro, of the direct insulinotropic effects of the gut hormones GIP and GLP-1 (6) . That slideshow presentation (digitally remastered*) is posted here (1MEMO 20251204_1).

The proceedings paper delivered at the 5th IPITA is included in the Notes (7) , as well as the referenced previous papers (8,9)

Notes

1. Van der Burg MPM, Guicherit OR, Scherft JP, Frölich M, Terpstra JL, Gooszen HG. Functie na intralienale transplantatie van eilandjes van Langerhans in de hond ( Function after intrasplenic transplantation of islets of Langerhans in dogs ). Surgeon days ’92 of the Dutch Surgery Society, Rotterdam (The Netherlands) May 21–22, 1992. In : Gut factors controlling pancreatic islets • 20240910 • Michel van der Burg • michelvanderburg•com • URL https://michelvanderburg.com/2024/09/10/gut-factors-controlling-pancreatic-islets-20240910/

2. Van der Burg MPM, Guicherit OR, Frölich M, Gooszen HG. Insulinotropic effects of cholecystokinin, gastric inhibitory polypeptide and glucagon-like peptide-1 during perifusion of short-term cultured canine isolated islets. Regul Pept. 1995 Dec 7;60(1):61-7. doi: 10.1016/0167-0115(95)00122-4. PMID: 8747785.

3. Metabolic control after canine islet transplantation. M.P.M. van der Burg, P.T.R. van Suylichem, O.R. Guicherit, J.H.M. van Deijnen, M. Frölich, and H.G. Gooszen (Universities of Leiden & Groningen, The Netherlands). Poster presented at the 13th Workshop of the AIDSPIT Study Group , Igls, Austria, January 23–25, 1994 • In : GLP-1 blood sugar regulation in islet transplants • AIDSPIT 1994 • Michel van der Burg • Miracles.Media • @1MEMO 20251114 • TakeNode 810cc881-d084-4d2e-b252-d432918b1946 • URL https://michelvanderburg.com/2025/11/14

4. Background of this work was posted in Dutch Islets Transplant Team • @1MEMO 20250125 • URL https://michelvanderburg.com/2025/01/25/dutch-islets-transplant-team-1memo-20250125/

5. Van der Burg MPM. Pancreatic islet transplantation: studies on the technique and efficacy of islet isolation and transplantation. (Doctoral Thesis, Leiden University, 1994), Paperback (1994, Nov 9) Boskoop: Van der Burg (ISBN 9080216410); E-book (2022, Oct 25) Boskoop: Michel van der Burg | Miracles•Media ( ISBN 9789080216402). Retrieved (Dec 4th, 2025) from Leiden University Scholarly Publications, Persistent URL https://hdl.handle.net/1887/3486604 .

6. Oral presentation : Van der Burg MPM, Van Suylichem PTR, Guicherit OR, Frölich M, Lemkes HHPJ, Gooszen HG. Glycemic control mechanisms after canine islet autografting. 5th International Congress on Pancreas and Islet Transplantation (IPITA), Miami Beach (USA) June 20, 1995.

7. 5th IPITA Proceedings publication : Van der Burg MPM, Van Suylichem PTR, Guicherit OR, Frölich M, Lemkes HHPJ, Gooszen HG. Glycemic control mechanisms after canine islet autografting. Transplant Proc. 1995 Dec;27(6):3187-8. PMID: 8539903. PDF available below PMID_8539903

PMID_8539903 Download

Referenced previous publications :

8. Van der Burg MPM, Gooszen HG. The metabolic efficiency of islet grafts: an overview. In: Islet transplantation — current status of clinical application and experimental results. Hesse UJ , Pichlmaier H, Eds., Lengerich Germany, Wolfgang Pabst Verlag, 1992, p.93–99. Pabst hash code 0383b3abad3ae774b146ea0425c2227a PDF available below 1MEMO_20251204_4

1MEMO_20251204_4 Download

9. Van der Burg MPM, Guicherit OR, Scherft JP, Lemkes HHPJ, Frölich M, Gooszen HG. Postprandial performance after canine islet transplantation: the importance of gut factors (Abstract). Neth J Med 1992; 41: A25. PDF available below 1MEMO_20251204_3

1MEMO_20251204_3 Download

Other previous publications :

10. Van der Burg MPM, Guicherit OR, Van Suylichem PTR, Frölich M, Van Deijnen JHM, Gooszen HG. Importance of the entero-insular axis for islet graft function (Abstract). Cell Transplant 1994; 3: 257. Abstract – Second International Congress of the Cell Transplant Society May 1–4, 1994 Hyatt Regency Hotel • Minneapolis, Minnesota . https://doi.org/10.1177/096368979400300302 (Abstracts published , posters not presented). PDF available below 10.1177_096368979400300302

10.1177_096368979400300302 Download

11. Chapter 8, Doctoral Thesis, Leiden University, November 1994 : Metabolic control after intrasplenic islet autotransplantation in dogs: ß-cell secretory capacity, insulin action, and the enteroinsular axis. Michael P.M. van der Burg, Paul T.R. van Suylichem, Onna R. Guicherit, Marijke Frölich, Herman H.P.J. Lemkes, and Hein G. Gooszen. In : Van der Burg MPM. Pancreatic islet transplantation: studies on the technique and efficacy of islet isolation and transplantation ( Chapter 8). (Doctoral Thesis, Leiden University, 1994), Paperback (1994, Nov 9) Boskoop: Van der Burg (ISBN 9080216410); E-book (2022, Oct 25) Boskoop: Michel van der Burg | Miracles•Media ( ISBN 9789080216402). Retrieved (Nov 24th, 2025) from Leiden University Scholarly Publications, Persistent URL https://hdl.handle.net/1887/3486604 .
Direct link to file Chapter 8 , URL https://scholarlypublications.universiteitleiden.nl/access/item%3A3486615/view .

12. Doctoral Thesis, Leiden University, November 1994 (Chapter 6) : lnsulinotropic properties of cholecystokinin, gastric inhibitory polypeptide, and glucagon-like peptide-1 during perifusion of short-term cultured canine isolated islets. Michael P.M. van der Burg, Onna R. Guicherit, Marijke Frölich and Hein G. Gooszen. In : Van der Burg MPM. Pancreatic islet transplantation: studies on the technique and efficacy of islet isolation and transplantation ( Chapter 6). (Doctoral Thesis, Leiden University, 1994), Paperback (1994, Nov 9) Boskoop: Van der Burg (ISBN 9080216410); E-book (2022, Oct 25) Boskoop: Michel van der Burg | Miracles•Media ( ISBN 9789080216402). Retrieved (Nov 24th, 2025) from Leiden University Scholarly Publications, Persistent URL https://hdl.handle.net/1887/3486604 .
Direct link to file Chapter 6 , URL https://scholarlypublications.universiteitleiden.nl/access/item%3A3486613/view

Full papers

13. Van der Burg MPM, Guicherit OR, Frölich M, Gooszen HG. Insulinotropic effects of cholecystokinin, gastric inhibitory polypeptide and glucagon-like peptide-1 during perifusion of short-term cultured canine isolated islets. Regul Pept. 1995 Dec 7;60(1):61-7. doi: 10.1016/0167-0115(95)00122-4. PMID: 8747785.

14. Van der Burg MPM, Van Suylichem PTR, Guicherit OR, Frölich M, Lemkes HHPJ, Gooszen HG. Glucoregulation after canine islet transplantation: contribution of insulin secretory capacity, insulin action, and the entero-insular axis. Cell Transplant. 1997 Sep-Oct;6(5):497-503. doi: 10.1177/096368979700600509. PMID: 9331501. PDF link https://pure.rug.nl/ws/portalfiles/portal/58359942/096368979700600509.pdf

PDF (CC-BY-NC) from publisher via ResearchGate – https://www.researchgate.net/publication/317805208_Glucoregulation_after_Canine_Islet_Transplantation_Contribution_of_Insulin_Secretory_Capacity_Insulin_Action_and_the_Entero-Insular_Axis

* 1MEMO 20251204_1 . Digitally remastered presentation, using the images from the original slides handout, and the handout of the text spoken during the original presentation , now read using my personal synthesized voice.

#GLP1 #GIP #diabetes #islets #transplant

Updates

Update 20260203 – added ResearchGate link ref 14

Citation info : Glycemic control mechanisms after canine islet autografting • IPITA 1995 • Michel van der Burg • Miracles.Media • @1MEMO 20251204 • URL https://michelvanderburg.com/2025/12/04

Saint Sepulcre Moments • Miracles Docs #8 • 20250918

Moments from a vibrant testimony and jazz by Simon Gronowski at the Saint-Sépulcre school in Liège, Belgium, 19 november 2013.

The Institut Saint-Sépulcre (now S2J School Center) hosted 3 sessions with Simon Gronowski that day for different age groups, including adults in the evening — and, in between, an intimate jazz moment was created in the surreal ambience of the school’s chapel.

Thanks to friends Philippe Renette (co-producer), Simon Gronowski, Koenraad Tinel (Photo Dieter Telemans featured in Die Welt , Saturday 16th Nov 2013 – Feinde wie wir, by Felix Stephan) and Patrick (assisting with sound), staff Marc Belleflamme and André Hérin, and teachers Christine Marchal, Ingrid Lothe, others, and the Saint-Sépulcre students.
Special thanks to the students Hélène, Charline, Tristan, Kimberley, Elodie, Farah, Esther, Estelle, Laetitia, Catherine, Tracy, and Pauline for making possible the unique events that month in 2013 for this Miracles film project.

Filmed by Michel van der Burg at the Station Liège-Guillemins, and Institut Saint-Sépulcre , Liège, Belgium, 19 november 2013.

Saint Sepulcre Moments | Miracles Docs #8 | Miracles•Media | 20250918

Notes

French talks with English subtitles in open captions (OC).

Miracles Docs #8 :

The first French edition was published in 2022 as Simon Stompin’ at the Saint Sépulcre | Miracles•Media | 20221119 | ISAN 0000-0007-329C-0008-C-0000-0001-0 .

The here presented, second, edition is titled ‘Saint Sepulcre Moments’ and has open captions (burned in) showing English subtitles.