Lancet Letter 1989 UW Solution Islet Isolation | 20220823


Lancet Letter 1989 UW Solution Islet Isolation | 20220823 | Michel van der Burg | michelvanderburg•com | June 1989 preparing first submission for publication as letter in the Lancet medical journal the new concept of using the UW solution ( the University of Wisconsin organ preservation solution) for isolation and complete purification of islets of Langerhans in the laboratory for transplantation in diabetic patients. Later that year that exciting discovery was presented at meetings in Minneapolis, USA, and Barcelona, Spain. Details in yesterday’s post. Submission for publication as a letter in the Lancet had had no succes 😉
Final draft text produced on my personal Macintosh ED and Imagewriter-II matrix printer with Geneva font.

TakeNode ID: 9f11f523-9b5f-47e8-be99-b242a1ba9b40

TAGS #Lancet #journal #UWS #UW #solution #preservation #organ #islet #isletofLangerhans #Langerhans #pancreas #poster #concept #purification #transplantation #congress #meeting #Minneapolis #Netherlands #Leiden #LUMC #AZL #Barcelona #Spain #LibreOffice #Vanilla #MacDraw #MacintoshED #512K #Imagewriter #TakeNode #1Memo #michelvanderburg

Minneapolis 1989 Poster UW Solution Islet Isolation | 20220822

Minneapolis 1989 Poster • 20240804 • michelvanderburg•com

September 1989 at a symposium of two international societies in Minneapolis, USA (1) , I presented this first poster on the ‘ invention ‘ of using the UW solution ( the University of Wisconsin organ preservation solution) during pancreatic islet isolation, with the exciting discovery of near-complete purification of islets of Langerhans in the laboratory for transplantation in diabetic patients.

The next month at a meeting in Barcelona, Spain, this rather radical new concept was introduced (2, 3). June 1989 submission for publication as a letter in the Lancet had had no succes 😉


Poster designed and produced on my personal Macintosh ED and Imagewriter-II matrix printer, allowing full width printing over multiple pages in landscape (a low cost do-it-yourself discovery by me, at a time when posters were prepared on poster boards by graphical professionals using photography and special lettering techniques for around $400). Original MacDraw II file conversion with LibreOffice Vanilla.

Notes

1) Van der Burg MPM, Gooszen HG, Ploeg RJ, Scherft JP, Field MJ, Guicherit OR, Terpstra JL, Van de Woude FT, Frölich M, Bruijn JA. Comparison of islet isolation techniques in dogs: Over 90% purified islets using UW solution. 4th International Symposium on Organ Procurement and Preservation and 2nd International Congress on Pancreatic and Islet Transplantation, Minneapolis (USA) September 17–22, 1989.

2) Van der Burg MPM, Gooszen HG, Ploeg RJ, Guicherit OR, Scherft JP, Terpstra JL, Bruijn JA, Frölich M. Pancreatic islet isolation with UW solution: a new concept. 4th Congress of the European Society for Organ Transplantation, Barcelona (Spain) November 1–4, 1989.

3) Van der Burg MPM, Gooszen HG, Ploeg RJ, Guicherit OR, Scherft JP, Terpstra JL, Bruijn JA, Frölich M. Pancreatic islet isolation with UW solution: a new concept. Transplant Proc 1990; 22: 2050–2051.

Updates

20240804 – This remastered 20240804 edition of the Minneapolis 1989 poster , now shows the original photo of the islet prep as posted at the meeting in 1989. In addition the correct line spacing is now restored.
The previous poster published online two years ago (20220822) showed a different photo print (higher magnification, and without the bar indicator) of the same islet prep, not the correct image.

20241211 – Minor text updates 

Citation info : Minneapolis 1989 Poster UW Solution Islet Isolation | 20220822 | Michel van der Burg | michelvanderburg•com | TakeNode 91d70715-3fb3-4380-906a-0daf1b5ddd6a

Human Islet Purification Miami 1998 • @1MEMO 20181102

Efficacy of the novel iodixanol-UWS density gradient for human islet purification

Slideshow (video) of my January 1999 oral presentation in Igls (Innsbruck), Austria, at the 18th Workshop of the AIDSPIT (Artificial Insulin Delivery Systems, Pancreas and Islet Transplantation) Study Group. (Now known as AIDPIT).

These results of this innovative islet purification method developed in our Leiden islet laboratory (LUMC) were the outcome of work I had done spring 1998 with the islet group of Camillo Ricordi in the “fast track” center for diabetes research at the Diabetes Research Institute in Miami , Florida, USA.

Notes

The slideshow (pdf) was first uploaded Nov. 11, 2010 at at Scribd , and Archive.org • URL http://archive.org/details/EfficacyOfTheNovelIodixanol-uwsDensityGradientForHumanIslet

Original video title (file name) : 20181102 ~ Human Islet Purification Miami 1998

Updates:


20241202 – Text updated with extra info. Youtube video in post replaced by Vimeo edition. Copied 1-memo post to michelvanderburg.com .

20251101 – Vimeo video replaced with Youtube copy . Added @1MEMO in post title and citation info

Citation info : Human Islet Purification Miami 1998 • Michel van der Burg • Miracles.Media • @1MEMO 20181102 • URL michelvanderburg.com/2018/11/02/ • TakeNode 3f2ec4d2-afe0-4580-b055-92a2f231a4fa