Close encounter – I was attacked later that day , when getting too close while taking such a portrait photo, but escaped falling backwards. Balinese long-tailed macaque, semi-wild in the Sacred Monkey Forest Sanctuary in Ubud , Bali, Indonesia, Sep. 2000.
Poster 13th Workshop of the AIDSPIT Study Group , Igls (Austria) January 23–25, 1994• Digitally remastered by author, publisher, M.P.M. van der Burg • Miracles•Media • 20251114 • TakeNode 810cc881-d084-4d2e-b252-d432918b1946 • #GLP1
GLP-1 blood sugar regulation in islet transplants
GLP-1 (glucagon-like peptide-1) is now well-known from the anti-diabetic drugs that mimic the action of this natural hormone GLP-1, to treat type 2 diabetes and obesity. They work by stimulating insulin release, reducing glucagon secretion, slowing stomach emptying, and suppressing appetite, which leads to lower blood sugar and weight loss.
May 1992 we were the first to show direct potentiation of the insulin response from isolated islets by a (near-)physiological dose of the gut hormone GLP-1 during perifusion (in vitro) of canine islets at 7.5-10 mM glucose levels (1,2).
Jan 1994 we next showed this incretin effect of GLP-1 also after islet transplantation (in vivo, in dogs) in this poster (3) and abstract (4) presented at the 13th Workshop of the AIDSPIT (aka AIDPIT) Study Group , Igls, Austria, January 23–25, 1994.
Background of the work was posted earlier this year (5) and the work was published Nov 1994 in my PhD thesis Pancreatic islet transplantation , available online (6).
Notes
1) Van der Burg MPM, Guicherit OR, Scherft JP, Frölich M, Terpstra JL, Gooszen HG. Function after intrasplenic transplantation of islets of Langerhans in dogs (translated from dutch: Functie na intralienale transplantatie van eilandjes van Langerhans in de hond). Surgeon days ’92 of the Dutch Surgery Society, Rotterdam (The Netherlands) May 21–22, 1992. In : Gut factors controlling pancreatic islets • 20240910 | Michel van der Burg | michelvanderburg•com URL https://michelvanderburg.com/2024/09/10/gut-factors-controlling-pancreatic-islets-20240910/
2) van der Burg MPM, Guicherit OR, Frölich M, Gooszen HG. Insulinotropic effects of cholecystokinin, gastric inhibitory polypeptide and glucagon-like peptide-1 during perifusion of short-term cultured canine isolated islets. Regul Pept. 1995 Dec 7;60(1):61-7. doi: 10.1016/0167-0115(95)00122-4. PMID: 8747785.
3) Metabolic control after canine islet transplantation. M.P.M. van der Burg, P.T.R. van Suylichem, O.R. Guicherit, J.H.M. van Deijnen, M. Frölich, and H.G. Gooszen (Universities of Leiden & Groningen, The Netherlands). Poster presented at the 13th Workshop of the AIDSPIT Study Group , Igls, Austria, January 23–25, 1994 •
4) Metabolic control after canine islet transplantation. Van der Burg M.P.M., Guicherit O.R., van Suylichem P.T.R., Frölich M., van Deijnen J.H.M. , Gooszen H.G. (Leiden, The Netherlands; Groningen, The Netherlands). Horm metab Res 1994; 26: 63. (Abstract). View/Download file 1MEMO_20251113_2
6) Michael P.M. van der Burg. Pancreatic islet transplantation: studies on the technique and efficacy of islet isolation and transplantation. (Doctoral Thesis, Faculty of Medicine, Leiden University Medical Center (LUMC) , Leiden University), Boskoop: M.P.M. van der Burg | Miracles.Media (ISBN electronic, pdf, 9789080216402 ; ISBN print 9789080216419, 9080216410), 1994: 192 p. URL Thesis Repository Leiden University https://hdl.handle.net/1887/3486604
PM – Recording of the 13th AIDSPIT seminar on lessons from clinical islet transplantation was posted yesterday (7).
Citation info : GLP-1 blood sugar regulation in islet transplants • AIDSPIT 1994 • Michel van der Burg • Miracles.Media • @1MEMO 20251114 • TakeNode 810cc881-d084-4d2e-b252-d432918b1946 • URL https://michelvanderburg.com/2025/11/14
Seminar on lessons from clinical islet transplantation
Chairman K. Federlin (Giessen, Germany) opened the seminar Tuesday, January 25, 1994 and David Scharp began with his lesson from the Center in St. Louis (USA) at the 13th Workshop of the AIDSPIT * Study Group , Igls, Austria, January 23–25, 1994.
Notes
Video image: Iodixanol-UWS purified human islets, stained with dithizone (March 18, 1999) • Michel van der Burg , Leiden Islet Laboratory LUMC .
Second, remastered, edition created from the 1st video edition published 20170208 via Vimeo at 1-memo.com .
* AIDSPIT later known as AIDPIT.
Recorded with Olympus mini-tape dictaphone, and re-recorded from the speaker of the dictaphone.
My presentations at the event
Cell preservation in University of Wisconsin solution during isolation of canine islets of Langerhans. Van der Burg M.P.M., Guicherit O.R., Frölich M., Gooszen H.G. (Leiden, The Netherlands) . Horm metab Res 1994; 26: 63. (Abstract). File 1MEMO_20251113_2
Metabolic control after canine islet transplantation. Van der Burg M.P.M., Guicherit O.R., van Suylichem P.T.R., Frölich M., van Deijnen J.H.M. , Gooszen H.G. (Leiden, The Netherlands; Groningen, The Netherlands). Horm metab Res 1994; 26: 63. (Abstract). File 1MEMO_20251113_2
Front page Acta Diabetologica • Download Abstract Below
Abstract published in Acta Diabetologica 1998 of Iodixanol-UWS Human Islet Purification in 1998 at the Diabetes Research Institute in Miami. Abstracts book of the 18th Workshop of the AIDSPIT Study Group in Igls, Austria, Jan 1999.
Van der Burg MPM, Ranuncoli A, Molano R, Kirlew T, Ringers J, Bouwman E, Ricordi C. Efficacy of the novel iodixanol-UWS density gradient for human islet purification (Abstract). Acta Diabetol 1998; 35: 247. View / Download abstract (file 1MEMO_20251102_1.pdf) below .
Abstract added in full post : Efficacy of the novel iodixanol-UWS density gradient for human islet purification • Igls Aidspit 1999 • 20241202 • URL michelvanderburg.com/2024/12/02 •
Citation info : Iodixanol-UWS Human Islet Purification 1998 Abstract • Michel van der Burg • Miracles.Media • @1MEMO 20251102 • URL michelvanderburg.com/2025/11/02/
Citation info : Youtube Top 50 • Hessel & Tess • Michel van der Burg • Miracles•Media • @1MEMO 20251024 • TakeNode d8fa14f3-c24a-4a6d-be9b-89436045bb64 / f407ea33-2b69-43ae-93af-f8d34516bdfa
#13 Most Viewed Today Musicians on YouTube featuring Duo Agua Azul
I joined YouTube with Channel012 on June 20, 2007 , soon after YouTube was purchased by Google late 2006 . My first public video was uploaded Dec 30, 2007 : ‘Fire Breather’.
The 2nd video was a high quality video : “Tiroler Fasnacht 2008 in Igls”. Traditional carnival in the streets in Austria. This was uploaded May 7, 2008.
Some days later I was contacted by Maybelline — a friend from the early 1970s when we both studied biology at Leiden University in Holland, with whom I had not had any contact since — who was wondering whether it was me ‘the Michel of the biology study, after I had left a comment signed ‘Michel’ at her YouTube channel (@maybellinebroek) with music videos.
I learned she had just started the duo Agua Azul together with pianist Thijmen Vonk, with already about 16 performances lined up, one just completed , and an upcoming talent show in theater Agnietenhof in Tiel, Holland, next Friday 16 May, 2008. Just in time, the afternoon before that talent show, we agreed I’d film the show, and a few hours before the performance, I received the stage setup. Unfortunately, I was late for the opening number… and then filming… and same night editing. Next day rushes were checked, and the evening of May 19 the uploads of 4 of the songs at Maybelline’s channel succeeded — just in time for a screening the next morning for an important venue, to determine if they want to book Agua Azul in Cultuurhuis Doorn…which they did.
Maybelline’s YouTube channel ranked #13 Most Viewed Today Musicians in the Netherlands within the first two days after uploading our Agua Azul videos. Channel ranking was #58 in Most Viewed (This Week) Musicians in the Netherlands – a week after uploading (20080526).
Notes
More recently, I uploaded remastered editions of those videos , and added a new video too, a video of the interview with Agua Azul on that “Open Podium” in the Agnietenhof Theatre in Tiel , Holland on Friday 16 May, 2008.
Start Agua Azul ~ Holland • @1MEMO 20180523 • Interview 10 years ago at the flying start of Maybelline’s Agua Azul with pianist Thijmen Vonk – May 2008 – by Stefka at the “Open Podium” in the “Agnietenhof Theatre” in Tiel , Holland • URL https://youtu.be/Dlqk02QvXu8
Um Dia Novo • Agua Azul • @1MEMO 20211109 • Concert by Agua Azul on May 16, 2008 in Agnietenhof Theatre, Tiel, Netherlands ~ Percussion: Thijmen Vonk ~ Words and Music: Maybelline Broekhuijsen | agua-azul.nl | Text inspired by the story “De Rivier” by Bert Bijl ~ Film : Michel van der Burg | Miracles•Media | Remastered 2nd edition of film first published May 19, 2008 • URL https://youtu.be/W_fpcewYFZY
Reunião • Agua Azul • @1MEMO 20211108 • Concert by Agua Azul on May 16, 2008 in Agnietenhof Theatre, Tiel, Netherlands ~ Piano: Thijmen Vonk ~ Words and Music: Maybelline Broekhuijsen | agua-azul.nl ~ Film : Michel van der Burg | Miracles•Media | Remastered 2nd edition of film first published May 19, 2008 • URL https://youtu.be/_XU0OgDN4Nw
Journey • Thijmen Vonk • @1MEMO 20211107 • Thijmen Vonk – the Dutch Piano Wizard – plays (and improvises on) his own composition ‘Journey’ at the Agua Azul concert May 16, 2008 in Agnietenhof Theatre, Tiel, Netherlands | agua-azul.nl ~ Film : Michel van der Burg | Miracles•Media | Remastered 2nd edition of film first published May 19, 2008 • https://youtu.be/j5Gb6fzKePs
Agua Azul is screening via channel @AguaAzulHolland
Citation info : Youtube Top 15 • Agua Azul • Michel van der Burg • Miracles•Media • @1MEMO 20251023 • TakeNode 3e68356b-e1ae-4a79-a8e4-abf513d61d0a / 29d4ed88-5551-42ff-8bd6-4c8269fe89b5