Shortly after starting our Islet Lab end 1986, I hand-picked and photographed this special big heart-shaped isolated islet of Langerhans with Uncle Scrooge McDuck’s ‘lucky #1 dime’ in mind.
(dutch : Dagobert Duck’s geluksdubbeltje). This ‘First Islet’ poster was pinned to the wall in my study in the (small) Islet Lab ‘wing’ in the Cell Biology building of the Leiden University Hospital.
It’s an Islet of Langerhans isolated from a rat pancreas. For pilot work, the first months while developing our islet project plan, islets were isolated from rat pancreases.
I had started developing our basic lab methods… like eg. measuring the insulin secretion capacity and insulin content of isolated islets. A custom-made glass pipet was used to hand-pick and transfer the islets to little polypropyleen ‘Eppendorf’ tubes for insulin secretion tests with glucose stimulation.
Citation info : Lucky #1 Islet • 20240811 • Michel van der Burg • michelvanderburg•com | TakeNode 5234a6e0-4565-4167-bb46-0f922c0b1d2a
September 1989 at a symposium of two international societies in Minneapolis, USA (1) , I presented this first poster on the ‘ invention ‘ of using the UW solution ( the University of Wisconsin organ preservation solution) during pancreatic islet isolation, with the exciting discovery of near-complete purification of islets of Langerhans in the laboratory for transplantation in diabetic patients.
Here the remastered 20240804 edition of that Minneapolis 1989 poster presentation.
The UWS data had been added ad hoc in the poster – that is , it wasn’t part of the accepted abstract. The first proceedings paper on our UWS work was also submitted at this meeting , and was published April ’90 (3).
A previous edition of the remastered poster was published here two years ago (2) but that edition had a different photo print (higher magnification, and without the bar indicator) of the purified islet preparation inserted, not the original image. This has been corrected now. In addition the original line spacing is now restored.
Notes
1) Van der Burg MPM, Gooszen HG, Ploeg RJ, Scherft JP, Field MJ, Guicherit OR, Terpstra JL, Van de Woude FT, Frölich M, Bruijn JA. Comparison of islet isolation techniques in dogs: Over 90% purified islets using UW solution. 4th International Symposium on Organ Procurement and Preservation and 2nd International Congress on Pancreatic and Islet Transplantation, Minneapolis (USA) September 17–22, 1989.
2) Minneapolis 1989 Poster UW Solution Islet Isolation | 20220822 | Michel van der Burg | michelvanderburg•com | URL https://michelvanderburg.com/2022/08/22
3). Van der Burg MPM, Gooszen HG, Ploeg RJ, Scherft JP, Field MJ, Guicherit OR, Terpstra JL, Van de Woude FJ, Frölich M, Bruijn JA. Comparison of islet isolation techniques in dogs: Over 90% purified islets using UW solution. Transplant Proc. 1990 Apr;22(2):795-6. PMID: 2158174. This paper appears to be not readily available online – a reprint copy is available here PMID_2158174 🔗
Leiden Islet Laboratory History • 20240803 | Michel van der Burg | michelvanderburg•com | TakeNode fad1be86-34f2-453f-b477-2abc62e467be
Summer 1985… start of our Leiden Islet Transplant Laboratory by Paul van Suylichem (right) and Michel van der Burg (middle), both from the Surgery department — wondering how to start here our islet lab in this space – a former weighing chamber (left : stable weighing table) made available by the Cell Biology department of the Leiden University, headed by Prof J.P. Scherft. Where to put our equipment… the laminar flow cabinet, large centrifuge, fridge, freezer, shaking waterbath, microscopes, and a lot of disposables coming ?
I had started working in 1981 for the Pancreas project. Pancreas transplantation research with the surgeon Hein Gooszen , working on his PhD (1), and surgeon Reinout van Schilfgaarde – who headed the project – and in 1985 also started this islet project.
Summer 1986, when Reinout van Schilfgaarde together with Paul van Suylichem moved to the Groningen University Hospital (2), Hein Gooszen and I decided to make a fresh start with the now operational Leiden Islet Lab…
Fifteen years of research later we were ready to roll with the isolation of human islets of Langerhans, in our new GMP facility in the Leiden Univerity Medical Center (LUMC). September 2001, the National Health Care Institute positively assessed our permit application for Transplantation of Islets of Langerhans in the LUMC (3,6), followed by approval May 2003 of the islet bank by the Health and Youth Care Inspectorate of the Ministry of Health, Welfare and Sport (VWS).
Notes
Post last update : 20241010-1611
Gooszen HG. Canine segmental pancreatic autotransplantation. Analysis of the effects of ductobliteration. Thesis, Leiden, 1984
Advies vergunningsaanvraag transplantatie Eilandjes van Langerhans | Op 27 september 2001 uitgebracht aan de minister van Volksgezondheid, Welzijn en Sport. | Rapport 01/71 | C.R. Smand, J.P. Verduijn / College voor Zorgverzekeringen. URL https://data.bibliotheken.nl/id/nbt/p229940978
Update 20240807. Added some history, and made minor changes.
Update 20240828 minor correction date (Fresh start lab ‘At the end of 1986’ changed to Summer 1986.)
Update 20241010, added : Press release Sep 27, 2001 by National Health Care Institute (CVZ). Transplantatie Eilandjes van Langerhans naar LUMC 27 september 2001. CVZ adviseert over vergunning. John van der Pas, persvoorlichter CVZ. Source : Razende Robot Reporter | Nieuwsbank Interactief Nederlands persbureau . Retrieved 20090313 from Nieuwsbank.nl (link expired, domain has new owner). 20241010 PDF (Ads , and author phone number redacted by M.P.M. van der Burg | Miracles•Media) file 20241010_CVZ • URL michelvanderburg.com/2024/10/10
Citation info : Leiden Islet Laboratory History • 20240803 | Michel van der Burg | michelvanderburg•com | TakeNode fad1be86-34f2-453f-b477-2abc62e467be
TRANSPORT XX — installation Brussels February 28th, 2009, Brussels. Day two, of my encounter with the TRANSPORT XX installation outside in the Royal park in Brussels, that presented 1200 photographic portraits of Jews deported from Malines (Belgium) to Auschwitz in 1943. One of the stills and establising video shots made that Saturday morning after finishing long take video recordings of the installation, during a walk from our hotel in the Leopold (European) Quarter via the Royal park direction the historic centre of Brussels. That weekend break in Brussels, today 15 years ago, turned out to be a turning point in my life. Two months later – April 19, 2009 – the film TRANSPORT XX — installation Brussels was published.
8. First Encounter TRANSPORT XX … | 20240227 | Michel van der Burg | Miracles•Media | URL https://michelvanderburg.com/2024/02/27 | TakeNode cf0dd64d-4512-4846-8bce-6b2d8cca24ef
9. Camera used for both photo and video (720p HD video) of the TRANSPORT XX installation in Brussels is the Sony DSC-T500 which has a CCD sensor – with global shutter – thus not affected by rolling shutter distortion while panning the installation.
Citation info : Encounter TRANSPORT XX … | 20240228 | Michel van der Burg | Miracles•Media | URL https://michelvanderburg.com/2024/02/28 | TakeNode a8317838-7470-4538-b788-40e6cc07b55a
February 28th, 2009, Brussels — my first encounter with the TRANSPORT XX installation in Brussels, that presented 1200 photographic portraits of Jews deported from Malines (Belgium) to Auschwitz in 1943. Turning point in my life. Two months later – April 19, 2009 – the film was published.
Citation info : First Encounter TRANSPORT XX … | 20240227 | Michel van der Burg | Miracles•Media | URL https://michelvanderburg.com/2024/02/27 | TakeNode cf0dd64d-4512-4846-8bce-6b2d8cca24ef
Click image for watching podcast video at 1memo.substack.com…
NL (dutch) – Podcast Première 1MEMO – Nederlandse editie. Introductie van het podcasting op 1MEMO. Publicatie op 1memo•substack•com is inclusief video. Gisteren (20240213) werd de Engelse editie (NL) geplaatst.
NL (dutch) – Podcast Première 1MEMO – Nederlandse editie. Introductie van het podcasting op 1MEMO. Publicatie op 1memo•substack•com is inclusief video. Gisteren (20240213) werd de Engelse editie (NL) geplaatst. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit 1memo.substack.com
TRANSCRIPTIE
Ciao ,
Welkom, bij deze eerste internationale podcast van 1MEMO.
Mijn naam is Michel van der Burg.
Vandaag is het woensdag 14 februari 2024. Valentijnsdag.
Ik wandel in het Groene Hart van Nederland…terwijl ik deze eerste 1 memo podcast maak in het Nederlands.
Tja … wat is zo’n 1-memo ?
In ‘t kort : gewoon ‘iets’… wat ik dagelijks publiceer .
Een foto, film – kort, lang – tekst, audio…
Niet persé dagelijks, dacht ik aanvankelijk… toen ik daar aan begon.
Maar ik doe ik dit nu eigenlijk dagelijks , al bijna 10 jaar…
Gestart in juni 2014 met publiceren in het Engels…. voor een internationaal publiek, hopelijk…
De focus is altijd op visueel werk, meest film.
Nu ik graag podcasting toevoeg, realiseer ik me plots dat het grootste deel van mijn materiaal in het Nederlands is – mijn moedertaal.
In filmwerk wordt dat zonodig vertaald, dus dat is geen probleem.
Maar een internationale podcast is anders…
Het podcasten hier zal in het Nederlands, Engels en Frans zijn.
Gisteren de première van de Engelse editie van deze post – en nu dan de Nederlandse première.
Ik zal de taal in de titels aangeven.
Tenslotte … waarom deze ① memo’s ?
Tja, voor een antwoord citeer ik hier graag de Nederlandse schrijfster Marja Pinckaers – uit haar boek 16 versie 61 :
‘Elke dag maak ik wat. Dan is er ‘s avonds iets op de wereld wat er ‘s ochtends niet was.
Of mischien toch, maar moest ik het nog zoeken en vond ik het •’
Bedankt voor het luisteren.
Ciao…
NOTES
Start Dailies | 20140626 | 1-memo•com
16 versie 61. Marja Pinckaers . Publ. Aspekt. ISBN 9789461535740 . Citaat : ” Elke dag maak ik wat. Dan is er ‘s avonds iets op de wereld wat er ‘s ochtends niet was. Of mischien toch, maar moest ik het nog zoeken en vond ik het. Uit.” — Gemma Edelsteen | Marja Pinckaers
What a Wonderful World. Simon Gronowski (piano) & TINT theater acteurs en publiek (zang) in het Brusselse Atelier Marcel Hastir , 2020. Audio van film : Wonderful World of Simon Gronowski | 20220804 | Michel van der Burg | Miracles•Media | URL https://1-memo.com/2022/08/04/wonderful-world-of-simon-gronowski-20220804/
Het Crescendo koor (dirigent : Urbain Van Asch) zingt Bella Ciao tijdens de 2016 Transport XX herdenking in Boortmeerbeek , Belgium. Audio van film : Bella Ciao … Transport XX | 20160417 | Michel van der Burg | Miracles•Media | URL https://1-memo.com/2016/04/17/bella-ciao-transport-xx/
Stem : Michel van der Burg. @1memo
Credit : Podcast Première 1MEMO – NL | 20240214 | 1MEMO | Michel van der Burg | Miracles•Media | URL https://1memo.substack.com | TakeNode b0bbaa54-2c3d-4ee6-b733-a7ec06fdd90c
Click image for watching the podcast video at 1memo.substack.com …
Podcast Premiere 1MEMO. Introduction on podcasting at 1MEMO. English edition. Published including video playing at 1memo•substack•com . Tomorrow , hopefully , the Dutch edition (NL) follows.
Podcast Premiere 1MEMO. Introduction on podcasting at 1MEMO. English edition. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit 1memo.substack.com
TRANSCRIPT
Ciao ,
Welcome , at this 1st international podcast , at 1MEMO.
My name is Michel van der Burg.
Today it’s Tuesday , Feb. 13, 2024 . I am walking in the Green Heart of Holland…while making this first 1 memo podcast.
Well , what is a 1 memo ?
In short — It’s just a thing…I publish daily. A photo, film, text, audio … Not necessarily daily …
But I have been doing this daily , actually , for almost 10 years…now…
Started June 2014. Publishing in english …. for an international public , hopefully…
The focus is on visual work, mostly film.
Now that I like to add podcasting, I suddenly realize , that most of my footage is in Dutch – my native language. In film work , that is translated , so , no problem.
However an international podcast is different .
Podcasting here will be in dutch, english, french .
Here first the english edition – tomorrow the dutch edition.
I will indicate the language in the titles.
So why these ① memo’s ?
Well , for an answer , I like to quote here the dutch author Marja Pinckaers ,
(my translation) :
Every day I make something. Then in the evening there’s something in the world that wasn’t there in the morning.
Or maybe it was there, but I still had to look for it and I found it •
Thank you for listening , …ciao
NOTES
Start Dailies | 20140626 | 1-memo•com
16 versie 61. Marja Pinckaers . Publ. Aspekt. ISBN 9789461535740 . Quote : ” Elke dag maak ik wat. Dan is er ‘s avonds iets op de wereld wat er ‘s ochtends niet was. Of mischien toch, maar moest ik het nog zoeken en vond ik het. Uit.” — Gemma Edelsteen | Marja Pinckaers
What a Wonderful World. Simon Gronowski (piano) & TINT theater actors and audience (singing) in Brussels’ Atelier Marcel Hastir , 2020. Audio from film : Wonderful World of Simon Gronowski | 20220804 | Michel van der Burg | Miracles•Media | https://1-memo.com/2022/08/04/wonderful-world-of-simon-gronowski-20220804/
The Crescendo choir (conductor : Urbain Van Asch) sings Bella Ciao during the 2016 Transport XX commemoration in Boortmeerbeek , Belgium. Audio from film : Bella Ciao … Transport XX | 20160417 | Michel van der Burg | Miracles•Media | URL https://1-memo.com/2016/04/17/bella-ciao-transport-xx/
Voice : Michel van der Burg. @1memo
Citation info : Podcast Premiere 1MEMO – EN | 20240213 | 1MEMO | Michel van der Burg | Miracles•Media | URL https://1memo.substack.com | TakeNode ddb6c544-bb38-4c4f-a208-9e4b21ba725c
