Tag Archives: ebook

Pancreatic islet transplantation Thesis Repository Leiden University | 20221125

Pancreatic islet transplantation Thesis Repository Leiden University | 20221125 | Michel van der Burg | Miracles•Media

Pancreatic islet transplantation , the doctoral thesis by Michel van der Burg – digital publication ISBN 9789080216402 – is freely available (Open Access) now in the Scholarly Publications repository of Leiden University. Persistent URL of this record https://hdl.handle.net/1887/3486604

The dissertation ‘Pancreatic islet transplantation’ was published first as a paperback in 1994 ( ISBN paperback 9789080216419 ) — and obviously that is considered virtually inaccessible in this digital age. Though it is still available ‘new’ — collectors item 😉
Last October the digital edition ISBN eBook (pdf) 9789080216402 has been produced and first released by the author / publisher Michel van der Burg at Miracles•Media as a free download , available from October 25th, 2022.

TAGS #repository #scholarly #publications #Leiden #University #pancreatic #islets #islet #isolation #beta @cells #doctoral #thesis #dissertation #digital #addendum #stellingen #propositions #ISBN9789080216402 #publish #science #donor #pancreas #insulin #therapy #clinical #Langerhans #Wisconsin #solution #UWS #purification #density #gradient #percoll #iodixanol #separation #transplantation #medicine #biology #diabetes #IDDM #laboratory #research #cure #LUMC #dissertation #PhD #Doctor #Philosophy #publisher #scan #ebook #book #ISBN #9789080216402 #9789080216419 #Holland #Netherlands #TakeNode #1Memo #michelvanderburg #MiraclesMedia

Viviane’s Story | eBook New Prints | 20221111

Viviane’s Story | eBook New Prints | 20221111

November 11, 2022 — Viviane’s Story by Viviane Yarom-Castegnier & Michel van der Burg was first published by Miracles.Media the night of April 19, 2019 as eBook (ePub) including video with a file size of 200 MB.

Now, the 2nd print of this eBook (ePub) is released – with the much smaller size of 60 MB ( same ISBN 9789493147003 ).
In addition now a PDF edition of the eBook is released with ISBN 9789493147010 .

You can download both these new eBooks of Viviane’s Story from the site Miracles.Media — both the ePUB (ISBN 978-94-93147-00-3) and PDF (ISBN 978-94-93147-01-0) editions. Link https://miracles.media/vivianesstory/

Viviane's Story
Escape from Transport XX...Born 6 Months Later

by 

Viviane Yarom-Castegnier & Michel van der Burg

On the night of the 19th of April in 1943 – Viviane escaped in the womb of her pregnant mother from the Twentieth Train heading for Auschwitz.
Isabella Weinreb-Castegnier was three-months pregnant when she jumped that night in Belgium from the fast moving 20th Death Train to Auschwitz.
It was Passover eve and full moon.

Isabella escaped with a broken wrist and bruises all over her body, but no other major injuries.
Her daughter Viviane – meaning “full of life”, and named so for her will to live and hold tight in her mother’s womb – was born six months later on October 30, 1943 in Brussels, Belgium.

This e-booklet presents Viviane’s story with amazing new insights discovered together with the Dutch-Belgian author-reporter Simone Korkus of the man that helped Isabella jump to freedom – Elias Gnazik.

Published April 19, 2019 by Miracles•Media together with co-publisher Richard Bloom Productions — With a foreword by Simone Korkus — ISBN 9789493147003

Stellingen | Addendum e-Book ISBN_9789080216402 | 20221026

Stellingen | Addendum e-Book ISBN_9789080216402 | 20221026 | Michel van der Burg | Miracles•Media

Free download available now of the Addendum e-book (pdf) ‘Propositions | Stellingen (dutch)’ belonging to the dissertation ‘Pancreatic islet transplantation’ by Michel P.M. van der Burg (addendum eBook ISBN 9789080216402) .

Download available at Miracles.Media page https://miracles.media/pancreatic-islet-transplantation-ebook-isbn-9789080216402/

Note : The Dutch dissertation system has a tradition of accompanying the generally very specialised PhD thesis with ten or more propositions (other ‘theses’), that should be ‘defensible’, and while at least some should be related to the dissertation, others generally reflect the PhD candidate’s broader interests, and the last one is often playful.

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Pancreatic islet transplantation | eBook ISBN 9789080216402

Pancreatic islet transplantation | eBook ISBN 9789080216402 | 20221025 | Michel van der Burg | Miracles•Media

Pancreatic islet transplantation : studies on the technique and efficacy of islet isolation and transplantation. PhD Thesis (English) by Michel P.M. van der Burg.

The doctoral thesis ‘Pancreatic islet transplantation’ was published first as a paperback in 1994 — and obviously that is considered virtually inaccessible in this digital age. Now this e-Book edition has been produced and released by the author / publisher Michel van der Burg | Miracles•Media as a free download , available from October 25th, 2022.

Preview & Download

Preview & download eBook ‘Pancreatic islet transplantation’ by Michel van der Burg | ISBN eBook (pdf) 978-90-802164-0-2 for free at the author’s / publishers’ site Miracles•Media here :
https://miracles.media/pancreatic-islet-transplantation-ebook-isbn-9789080216402/

Support – For people who would like to also support my work – you can … ‘Buy me a coffee’ there too 😉

eBook details

Title : Pancreatic islet transplantation : Studies on the technique and efficacy of islet isolation and transplantation

Author : Michel P.M. van der Burg

Publisher : M.P.M. van der Burg | Miracles.Media

Genre : Medicine Technology & Science & Nature

Released : October 25, 2022

Language : EN English & Dutch summary

Length : 192 pages / 68 MB

Format : PDF (full access, no DRM, searchable PDF – designed for long term accessibility and archive PDF/A-1b – PDF/UA)

Version : Reprinted 1st edition (2nd impression) as eBook (pdf ISBN 9789080216402) by author / publisher M.P.M. van der Burg from scanned paperback published in 1994 by M.P.M. van der Burg (ISBN paperback 9789080216419).

Requirements : You can view this book on any device, best with a tablet or larger screen.

Addendum : Propositions | Stellingen (dutch) – published – release here will follow later.

Review / Award : Glaxo Wellcome Gastrointestinal Research Award – 2nd Prize – awarded October 5, 1995 to Michel P.M. van der Burg for the dissertation “Pancreatic islet transplantation” (received at the Fall meeting of the Dutch Gastroenterology Society, Veldhoven, The Netherlands)

File name : 9789080216402_ISBN.pdf

TakeNode ID : b9a348fd-9f3e-4f02-af51-e1ab25d61522

Publisher’s description

Pancreatic islet transplantation by a new method is introduced here : the isolation of islets in an organ preservation solution, the University of Wisconsin solution. A new concept allowing for the first time large-scale isolation and transplantation of consistently near 100% pure islets of Langerhans in a preclinical dog model with fasting normoglycemia up to 3 years posttransplant. Detailed metabolic studies demonstrated normal insulin levels after meals with preservation of gut hormone action stimulating insulin secretion at the mild hyperglycemia after meals. The introduction of the University of Wisconsin solution organ preservation solution for islet isolation at the start of these studies in 1989 is a new concept … and has been shown by now in 2022 , world-wide , to make the future of islet isolation and transplantation methods for insulin-dependent diabetes mellitus (IDDM).

TAGS #ebook #transplantation #islets #technology #thesis #medicine #ISBN9789080216402 #book #release #distibution #cover #FrenchFlap #flap #publish #blurb #science #donor #pancreas #insulin #therapy #clinical #isletsofLangerhans #isolation #University #Wisconsin #solution #UWS #density #gradient #separation #biology #diabetes #IDDM #laboratory #research #cure #Leiden #University #LUMC #dissertation #PhD #DoctorofPhilosophy #publisher #scan #ISBN9789080216419 #Holland #Netherlands #TakeNode #MiraclesMedia #1Memo #michelvanderburg

Cover | Pancreatic islet transplantation | ISBN 9789080216402

Cover | Pancreatic islet transplantation | ISBN 9789080216402 | 20221024 | Michel van der Burg | Miracles•Media | PUBLISHED ! Here the full cover with a French flap back-cover of the e-Book (pdf) edition of my doctoral thesis ‘Pancreatic islet transplantation’ – ISBN 9789080216402 – published and registered today, Oct 24th, 2022 . In short : Pancreatic islet isolation in the University of Wisconsin solution is a new concept introduced here … allowing transplantation of pure islets as an effective treatment in insulin-dependent diabetes. Distribution of the e-Book and full information follows this week.

TakeNode ID: c50c9112-5763-4117-b31a-e818723e18a2

TAGS #cover #FrenchFlap #flap #publish #blurb #science #donor #pancreas #insulin #therapy #clinical #isletsofLangerhans #isolation #UniversityofWisconsin #solution #UWS #density #gradient #separation #transplantation #medicine #biology #diabetes #IDDM #laboratory #research #cure #LeidenUniversity #LUMC #dissertation #PhD #DoctorofPhilosophy #publisher #scan #ebook #book #ISBN9789080216402 #ISBN9789080216419 #Holland #Netherlands #TakeNode #MiraclesMedia #1Memo #michelvanderburg

Blurb | Pancreatic islet transplantation | 20221023

Blurb | Pancreatic islet transplantation | 20221023 | Michel van der Burg | Miracles•Media | French flap interior of paperback back cover with illustration of islet isolation and transplantation in the doctoral thesis Pancreatic islet transplantation – ISBN 9789080216402. Studies aiming at transplantation of the pancreatic Islets of Langerhans to prevent, postpone or ameliorate the long-term crippling complications of insulin-dependent diabetes mellitus (IDDM). Paperback published in 1994 ISBN 9789080216419 | 9080216410 , later this month published as eBook (pdf) ISBN 9789080216402.

Illustration of Islet Isolation and Transplantation
(Captions at last page of the dissertation)

1. Paul Langerhans
2. Section of the normal dog pancreas showing islets stained reddish-brown (immunostained for insulin)
3. The author, watching the dog islet isolation procedure in the Minneapolis surgical research laboratory
4. Start of the operation in the dog (From left to right: Professor Hein G. Gooszen, Ms. M. Jane Field (Minneapolis), and Dr. Onno R. Guicherit, at our surgical laboratory)
5. The pancreas is removed
6. Infusion of the collagenase solution via the ducts in the dog pancreas – collagenase leaking from the pancreas is recirculated using a pump (Islet laboratory, at the Department of Cell Biology and Histology, Leiden)
7. During collagenase digestion at 37-39°C the pancreas falls apart (non-stained pancreatic exocrine tissue and free-ed small blood vessel, at low magnification)
8. Dissociated pancreatic tissue
9. Tissue is further dispersed by aspiration in a syringe, and sieved to remove undigested fragments, ducts and vessels ~ demonstrated by Ms. Jane Field at our islet laboratory.
10. Tissue suspension demonstrating low purity of the islets (stained red by dithizone) obtained by dextran gradient separation after isolation in the RPMI tissue culture solution (dark-brown exocrine fragments remain unstained)
11. Pure islet suspension (after dithizone staining) obtained by density separation in Percoll gradients (in University of Wisconsin solution) after islet isolation in the University of Wisconsin solution (islets are only slightly stained due to poor diffusion over the cell membrane in the preservation solution)
12. Section of highly purified islets obtained by dextran density separation after isolation in the University of Wisconsin solution
13. Islets are autotransplanted by infusion in the spleen of the dog
14. Transplanted islet in section of the spleen of one of the dogs shortly after the onset of fasting hyperglycemia at three months posttransplant (immunostained for insulin)
15. Highly purified human islets obtained by Percoll density separation after isolation in the University of Wisconsin solution (immunostained with gold for insulin; not counterstained)

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Reprint | 20221022


Reprint | 20221022 | Michel van der Burg | 1-memo•com | Silent film. Scanning for an ebook reprint – ISBN 9789080216402 – of the doctoral thesis Pancreatic islet transplantation. Studies on the isolation and transplantation of the pancreatic Islets of Langerhans to prevent, postpone or ameliorate the long-term crippling complications of insulin-dependent diabetes mellitus (IDDM). First published as a paperback in 1994 ISBN 9080216410 / 9789080216419 , and later this month published as eBook (pdf). TakeNode ID: 777e40a7-c148-4832-a24a-ff599c1845c5

TAGS #publish #science #donor #pancreas #insulin #therapy #clinical #islets of Langerhans #isolation #transplantation #medicine #biology #diabetes #IDDM #laboratory #research #cure #Leiden University #LUMC #dissertation #PhD #Doctor of Philosophy #publisher #scan #ebook #book #ISBN #9789080216402 #9789080216419 #Holland #Netherlands #TakeNode #1Memo #michelvanderburg